Genetic recombination in wild-type poliovirus
نویسندگان
چکیده
منابع مشابه
Wild Poliovirus Type 1, Central African Republic
1498 Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 11, No. 9, September 2005 in the neutralization and blocking ELISA assays, mostly because of SLEV. Complete test results from these horses, as well as from Colombian cattle and chickens, will be presented elsewhere. These serologic data should be considered indirect evidence of WNV activity in Colombia. We encourage Colombian human and ...
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Genetic recombination of plus-strand RNA viruses is an important process for promoting genetic variation. By using genetically marked poliovirus RNAs, we have demonstrated that genetic recombination can occur in a cell-free system that generates infective virus from added poliovirus RNA. Recombinant polioviruses were isolated, and the region of crossing over was roughly mapped. Recombinants cou...
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BACKGROUND Mucosal immunity induced by oral poliovirus vaccine (OPV) is imperfect and potentially allows immunized individuals to participate in asymptomatic wild-type poliovirus transmission in settings with efficient fecal-oral transmission of infection. METHODS We examined the extent of asymptomatic wild-type poliovirus transmission in India by measuring the prevalence of virus in stool sa...
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The emergence of circulating vaccine-derived poliovirus (cVDPV) strains in suboptimally vaccinated populations is a serious threat to the global poliovirus eradication. The genetic determinants for the transmissibility phenotype of polioviruses, and in particularly of cVDPV strains, are currently unknown. Here we describe the fecal excretion of wild-type poliovirus, oral polio vaccine, and cVDP...
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In 1988, the World Health Assembly resolved to eradicate polio worldwide. Since then, four of the six World Health Organization (WHO) regions have been certified as polio-free: the Americas in 1994, the Western Pacific Region in 2000, the European Region in 2002, and the South-East Asia Region in 2014. Currently, nearly 80% of the world's population lives in areas certified as polio-free. Certi...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2002
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-83-12-3103